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Sanofi-aventis and Exelixis, Inc. have entered a global license agreement for XL147 and XL765 and a broad collaboration for the discovery of inhibitors of phosphoinositide-3 kinase (PI3K) for the treatment of cancer.
May 28, 2009
By: Tim Wright
Editor-in-Chief, Contract Pharma
Sanofi-aventis and Exelixis, Inc. have entered a global license agreement for XL147 and XL765 and a broad collaboration for the discovery of inhibitors of phosphoinositide-3 kinase (PI3K) for the treatment of cancer. The PI3K pathway in human tumors is related to promoting cell proliferation, survival and resistance to chemotherapy and radiotherapy. Under the license, Sanofi-aventis will have a worldwide exclusive license to XL147 and XL765, which are currently in Phase I and Phase Ib/II tri...
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